Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.72 |
| ▸ | GAA | P10253 | 2/20 | 0.72 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | DHFR | P00374 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARD | Q03181 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2095593 | 0.86 | CA2 (1.00) | CA2ALDH1A1GAACYP19A1ATM | |
| SCHEMBL18214084 | 0.85 | ALDH1A1 (0.85) | CA2ALDH1A1GAACYP19A1ATM | |
| SCHEMBL273470 | 0.84 | ALDH1A1 (1.00) | CA2ALDH1A1GAACYP19A1ATM | |
| SCHEMBL30541678 | 0.84 | ALDH1A1 (1.00) | CA2ALDH1A1GAACYP19A1ATM | |
| SCHEMBL6865547 | 0.84 | GAA (1.00) | CA2ALDH1A1GAACYP19A1ATM | |
| SCHEMBL9828253 | 0.83 | CA2 (0.77) | CA2ALDH1A1GAACYP19A1ATM | |
| SCHEMBL29449205 | 0.82 | CA2 (0.91) | CA2ALDH1A1GAACYP19A1ATM | |
| SCHEMBL28164756 | 0.82 | CA2 (0.91) | CA2ALDH1A1GAACYP19A1ATM | |
| SCHEMBL5357864 | 0.80 | CA2 (0.61) | CA2ALDH1A1GAACYP19A1ATM | |
| SCHEMBL12110739 | 0.80 | CA2 (0.59) | CA2ALDH1A1GAACYP19A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162359-A | ANTIHYPERLIPOPROTEINEMIC 5-BENZYL SUBSTITUTED-BENZIMIDAZOLINE-2-THION DERIVATIVES | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1992-11-10 | — | — | US | disclosed |
| EP-0474109-A1 | New 5-benzyl-substituted benzimidazolin-2-thion derivatives and process for their preparation | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1992-03-11 | — | — | EP | disclosed |