Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.47 |
| ▸ | PRNP | P04156 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9660829 | 0.88 | POLB (0.49) | ABL1POLBHSD17B10CYP1A2SMN1; SMN2 | |
| SCHEMBL5226731 | 0.86 | ABL1 (0.50) | ABL1POLBHSD17B10CYP1A2SMN1; SMN2 | |
| SCHEMBL9660805 | 0.84 | HSD17B10 (0.50) | POLBHSD17B10CYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL9661037 | 0.84 | KDM4E (0.54) | POLBHSD17B10CYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL28440107 | 0.82 | ABL1 (0.56) | ABL1POLBHSD17B10CYP1A2SMN1; SMN2 | |
| SCHEMBL4071201 | 0.80 | ABL1 (0.60) | ABL1POLBHSD17B10CYP1A2SMN1; SMN2 | |
| SCHEMBL11093884 | 0.79 | MEN1 (0.50) | POLBCYP1A2ALDH1A1CYP3A4TDP1 | |
| SCHEMBL25826611 | 0.78 | ABL1 (0.63) | ABL1HSD17B10CYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL9660330 | 0.78 | HSD17B10 (0.77) | POLBHSD17B10CYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL9658942 | 0.78 | ALDH1A1 (0.53) | POLBHSD17B10CYP1A2SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118680-A | COMBATING ENDOPARASITES WITH 3-HYDROXYBENZOTHIOPHENES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | disclosed |