Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.63 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4071201 | 0.85 | ABL1 (0.60) | ABL1NR4A2RXFP1MAPTL3MBTL1 | |
| SCHEMBL28440107 | 0.81 | ABL1 (0.56) | ABL1NR4A2RXFP1MAPTL3MBTL1 | |
| SCHEMBL9660296 | 0.78 | ABL1 (0.53) | ABL1NR4A2RXFP1MAPTL3MBTL1 | |
| SCHEMBL2473934 | 0.78 | ABL1 (0.53) | ABL1NR4A2RXFP1MAPTL3MBTL1 | |
| SCHEMBL9660294 | 0.78 | ABL1 (0.53) | ABL1NR4A2RXFP1MAPTL3MBTL1 | |
| SCHEMBL9323068 | 0.78 | ABL1 (0.53) | ABL1NR4A2RXFP1MAPTL3MBTL1 | |
| SCHEMBL6100118 | 0.78 | ABL1 (0.70) | ABL1NR4A2RXFP1MAPTL3MBTL1 | |
| SCHEMBL771687 | 0.77 | ABL1 (1.00) | ABL1NR4A2RXFP1MAPTSMN1; SMN2 | |
| SCHEMBL4068751 | 0.77 | ABL1 (0.51) | ABL1NR4A2RXFP1MAPTL3MBTL1 | |
| SCHEMBL7754027 | 0.77 | HSD17B10 (0.62) | MAPTL3MBTL1SMN1; SMN2RAB9ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3880666-B1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS AG (CH) | 2023-06-28 | — | — | EP | disclosed |