Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9660740 | 0.86 | NPC1 (0.41) | KMT2ANPC1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL9661535 | 0.84 | KMT2A (0.40) | KMT2ANPC1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL9660439 | 0.84 | HPGD (0.41) | KMT2ANPC1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL9660896 | 0.82 | HPGD (0.39) | KMT2ANPC1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL9660775 | 0.80 | KMT2A (0.47) | KMT2ANPC1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL9660813 | 0.78 | SMN1; SMN2 (0.51) | KMT2ANPC1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL9661513 | 0.75 | NPC1 (0.45) | KMT2ANPC1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL9661603 | 0.75 | NPC1 (0.50) | KMT2ANPC1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL9660722 | 0.72 | KMT2A (0.43) | KMT2ANPC1SMN1; SMN2RAB9APOLB | |
| SCHEMBL9660407 | 0.71 | ALDH1A1 (0.31) | MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520274-A2 | 2-(-4-substituted-phenylhydrazino)-2-thiazoline and 2-(-4-substituted phenylazo)-2-thiazoline, their preparation and their use against ectoparasites | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |