Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9660775 | 0.82 | KMT2A (0.47) | SMN1; SMN2ALOX12MAPTTSHRKMT2A | |
| SCHEMBL9661513 | 0.77 | NPC1 (0.45) | SMN1; SMN2ALOX12MAPTTSHRKMT2A | |
| SCHEMBL9660740 | 0.77 | NPC1 (0.41) | SMN1; SMN2MAPTTSHRKMT2AHPGD | |
| SCHEMBL9660896 | 0.73 | HPGD (0.39) | SMN1; SMN2ALOX12MAPTTSHRKMT2A | |
| Hydrochloric Acid SCHEMBL11749763 | 0.71 | POLB (0.68) | SMN1; SMN2MAPTKMT2AHPGDLMNA | |
| SCHEMBL9660809 | 0.69 | APP (0.40) | SMN1; SMN2ALOX12MAPTTSHRHPGD | |
| SCHEMBL10457449 | 0.67 | APP (0.59) | ALDH1A1 | |
| SCHEMBL10458189 | 0.62 | ALDH1A1 (0.57) | MAPTGAAALDH1A1 | |
| SCHEMBL10458215 | 0.61 | APP (0.53) | MAPTALDH1A1 | |
| SCHEMBL9690715 | 0.60 | POLB (0.44) | SMN1; SMN2MAPTKMT2AHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520274-A2 | 2-(-4-substituted-phenylhydrazino)-2-thiazoline and 2-(-4-substituted phenylazo)-2-thiazoline, their preparation and their use against ectoparasites | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |