Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | BPTF | Q12830 | 1/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9658058 | 0.92 | ALDH1A1 (0.49) | ALDH1A1PGRGAAPTGS1MAPK1 | |
| SCHEMBL9659126 | 0.90 | ALDH1A1 (0.45) | ALDH1A1PGRGAAPTGS1MAPK1 | |
| SCHEMBL9659373 | 0.90 | ALDH1A1 (0.47) | ALDH1A1PGRGAAPTGS1MAPK1 | |
| SCHEMBL9660373 | 0.90 | HSD17B10 (0.43) | ALDH1A1PGRGAAPTGS1MAPK1 | |
| SCHEMBL9660610 | 0.88 | ALDH1A1 (0.53) | ALDH1A1PGRGAAPTGS1MAPK1 | |
| SCHEMBL9655015 | 0.88 | ALDH1A1 (0.53) | ALDH1A1PGRGAAPTGS1MAPK1 | |
| SCHEMBL9659170 | 0.87 | HSD17B10 (0.43) | ALDH1A1PGRGAAPTGS1MAPK1 | |
| SCHEMBL9660021 | 0.86 | SLC2A1 (0.43) | HSD17B10SLC2A1LMNAMAPTHTT | |
| SCHEMBL9628345 | 0.85 | HTT (0.56) | GAAHSD17B10SLC2A1LMNAMAPT | |
| SCHEMBL9657987 | 0.83 | ALDH1A1 (0.50) | ALDH1A1PGRGAAPTGS1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155132-A | Nonsteroidal antiinflammatory agents; treating psoriasis | SYNTEX (U.S.A.) INC. (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |
| US-4758587-A | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-07-19 | — | — | US | disclosed |