Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9657987 | 0.95 | ALDH1A1 (0.50) | ALDH1A1PGRGAAPTGS1MAPK1 | |
| SCHEMBL9660610 | 0.94 | ALDH1A1 (0.53) | ALDH1A1PGRGAAPTGS1MAPK1 | |
| SCHEMBL9660583 | 0.88 | ALDH1A1 (0.47) | ALDH1A1PGRGAAPTGS1MAPK1 | |
| SCHEMBL9660373 | 0.88 | HSD17B10 (0.43) | ALDH1A1PGRGAAPTGS1MAPK1 | |
| SCHEMBL9659895 | 0.85 | SLC2A1 (0.42) | ALDH1A1PGRGAAPTGS1MAPK1 | |
| SCHEMBL9659126 | 0.85 | ALDH1A1 (0.45) | ALDH1A1PGRGAAPTGS1MAPK1 | |
| SCHEMBL9660331 | 0.85 | TTR (0.45) | ALDH1A1PGRGAAPTGS1MAPK1 | |
| SCHEMBL9659017 | 0.85 | ALDH1A1 (0.43) | ALDH1A1PGRGAAPTGS1MAPK1 | |
| SCHEMBL9659170 | 0.85 | HSD17B10 (0.43) | ALDH1A1PGRGAAPTGS1MAPK1 | |
| SCHEMBL9658069 | 0.84 | NCEH1 (0.51) | ALDH1A1GAAPLK1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | claimed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | claimed |
| US-5134161-A | Enzyme inhibitors for skin disorders, antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |