Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 2/20 | 0.40 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9659352 | 0.90 | HTT (0.41) | IMPDH2IMPDH1PLK1HTTKDM4E | |
| SCHEMBL9657987 | 0.84 | ALDH1A1 (0.50) | PLK1HTTALOX15KDM4ECYP1A2 | |
| SCHEMBL9660357 | 0.82 | ALDH1A1 (0.44) | HTTKDM4ECYP1A2CYP2C9LMNA | |
| SCHEMBL9628421 | 0.81 | ELANE (0.45) | PLK1HTTALOX15KDM4ETSHR | |
| SCHEMBL9659345 | 0.80 | HSD17B10 (0.46) | PLK1HTTALOX15KDM4ECYP1A2 | |
| SCHEMBL9658188 | 0.80 | MEN1 (0.43) | PLK1HTTKDM4ELMNAATM | |
| SCHEMBL9659078 | 0.80 | ALDH1A1 (0.54) | HTTKDM4ECYP1A2CYP2C9ATM | |
| SCHEMBL9659017 | 0.80 | ALDH1A1 (0.43) | PLK1HTTALOX15MAPK14KDM4E | |
| SCHEMBL9655015 | 0.79 | ALDH1A1 (0.53) | PLK1HTTKDM4ECYP1A2CYP2C9 | |
| SCHEMBL9627466 | 0.79 | HTT (0.61) | HTTALOX15KDM4ECYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155132-A | Nonsteroidal antiinflammatory agents; treating psoriasis | SYNTEX (U.S.A.) INC. (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |
| US-4758587-A | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-07-19 | — | — | US | disclosed |