Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.30 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.30 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9661910 | 0.89 | SIGMAR1 (0.43) | SIGMAR1SLC6A2SLC6A4OPRD1GNAI3 | |
| SCHEMBL9660844 | 0.87 | SIGMAR1 (0.40) | SIGMAR1SLC6A2SLC6A4GNAI3GNAO1 | |
| SCHEMBL9660531 | 0.86 | GNAO1 (0.40) | SIGMAR1GNAI3GNAO1GNAI1 | |
| SCHEMBL9661103 | 0.86 | GNAO1 (0.40) | SIGMAR1GNAI3GNAO1GNAI1 | |
| SCHEMBL9660116 | 0.86 | GNAO1 (0.40) | SIGMAR1GNAI3GNAO1GNAI1 | |
| SCHEMBL9661714 | 0.86 | GNAO1 (0.40) | SIGMAR1GNAI3GNAO1GNAI1 | |
| SCHEMBL9660265 | 0.86 | GNAO1 (0.40) | SIGMAR1GNAI3GNAO1GNAI1 | |
| SCHEMBL9660732 | 0.86 | GNAO1 (0.40) | SIGMAR1GNAI3GNAO1GNAI1 | |
| SCHEMBL9660609 | 0.86 | GNAO1 (0.40) | SIGMAR1GNAI3GNAO1GNAI1 | |
| SCHEMBL9660916 | 0.86 | GNAO1 (0.40) | SIGMAR1GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0517262-A1 | Trifluorothymidine derivatives, process for producing the same and anti-cancer agent containing the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-12-09 | — | — | EP | disclosed |