Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 9/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9657973 | 1.00 | CNR1 (0.46) | CNR1CNR2MEN1NR1I2LMNA | |
| SCHEMBL9657991 | 0.96 | SLC2A1 (0.44) | CNR1CNR2MEN1NR1I2LMNA | |
| SCHEMBL9659029 | 0.91 | CNR1 (0.46) | CNR1CNR2MEN1NR1I2LMNA | |
| SCHEMBL9658002 | 0.91 | CNR1 (0.46) | CNR1CNR2MEN1NR1I2LMNA | |
| SCHEMBL9659348 | 0.91 | ALDH1A1 (0.44) | CNR1CNR2MEN1LMNAMAPT | |
| SCHEMBL9659389 | 0.87 | SLC2A1 (0.45) | CNR1CNR2THRATHRBEPHX1 | |
| SCHEMBL9658025 | 0.86 | CNR1 (0.47) | CNR1CNR2MEN1NR1I2LMNA | |
| SCHEMBL9657883 | 0.86 | CNR1 (0.47) | CNR1CNR2MEN1NR1I2LMNA | |
| SCHEMBL9660327 | 0.86 | HTT (0.50) | CNR1CNR2MEN1NR1I2LMNA | |
| SCHEMBL9660579 | 0.85 | ALDH1A1 (0.47) | LMNAALDH1A1PGRGAAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155132-A | Nonsteroidal antiinflammatory agents; treating psoriasis | SYNTEX (U.S.A.) INC. (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |
| US-4758587-A | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-07-19 | — | — | US | disclosed |