Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 3/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9659895 | 0.94 | SLC2A1 (0.42) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL9660688 | 0.91 | CNR1 (0.46) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL9657973 | 0.91 | CNR1 (0.46) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL9659865 | 0.91 | ALDH1A1 (0.47) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL9660579 | 0.89 | ALDH1A1 (0.47) | ALDH1A1HSD17B10GAAPGRPTGS1 | |
| SCHEMBL9657991 | 0.88 | SLC2A1 (0.44) | CNR1CNR2MAPTSLC2A1LMNA | |
| SCHEMBL9658056 | 0.87 | NCEH1 (0.42) | ALDH1A1CNR1CNR2NPC1RAB9A | |
| SCHEMBL9659430 | 0.86 | FAAH (0.45) | ALDH1A1GAANPC1RAB9AMAPT | |
| SCHEMBL9659324 | 0.85 | CNR1 (0.44) | ALDH1A1HSD17B10GAAMAPK1CNR1 | |
| SCHEMBL9659343 | 0.85 | FAAH (0.46) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155132-A | Nonsteroidal antiinflammatory agents; treating psoriasis | SYNTEX (U.S.A.) INC. (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |
| US-4758587-A | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-07-19 | — | — | US | disclosed |