Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 11/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9660769 | 0.82 | MAPT (0.36) | SMN1; SMN2TSHRALOX12MAPTLMNA | |
| SCHEMBL11747051 | 0.72 | ALDH1A1 (0.53) | SMN1; SMN2MAPTLMNA | |
| SCHEMBL9660717 | 0.72 | NPC1 (0.44) | TSHRMAPT | |
| SCHEMBL9660813 | 0.69 | SMN1; SMN2 (0.51) | SMN1; SMN2TSHRALOX12MAPTHPGD | |
| SCHEMBL9660718 | 0.69 | ALDH1A1 (0.40) | TSHRLMNA | |
| SCHEMBL10457449 | 0.67 | APP (0.59) | APP | |
| SCHEMBL21556921 | 0.62 | APP (0.56) | APPTSHRMAPTL3MBTL1 | |
| SCHEMBL9689560 | 0.62 | ALDH1A1 (0.36) | SMN1; SMN2LMNA | |
| SCHEMBL13420112 | 0.62 | APP (0.82) | APP | |
| SCHEMBL15199277 | 0.62 | APP (0.82) | APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520274-A2 | 2-(-4-substituted-phenylhydrazino)-2-thiazoline and 2-(-4-substituted phenylazo)-2-thiazoline, their preparation and their use against ectoparasites | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |