Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10492734 | 0.84 | MEN1 (0.81) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL9367728 | 0.82 | MEN1 (0.79) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL9659777 | 0.81 | MEN1 (0.71) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL9659976 | 0.79 | ALDH1A1 (0.71) | MEN1KMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL3277444 | 0.78 | ALDH1A1 (0.58) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL23483766 | 0.77 | MEN1 (0.70) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL9660225 | 0.77 | MEN1 (0.69) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL8701782 | 0.73 | PSMB8 (0.68) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL1149394 | 0.71 | IDO1 (0.58) | KMT2AALDH1A1TSHRHTTCYP3A4 | |
| SCHEMBL11410252 | 0.71 | IDO1 (0.58) | KMT2AALDH1A1TSHRHTTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162359-A | ANTIHYPERLIPOPROTEINEMIC 5-BENZYL SUBSTITUTED-BENZIMIDAZOLINE-2-THION DERIVATIVES | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1992-11-10 | — | — | US | claimed |
| EP-0474109-A1 | New 5-benzyl-substituted benzimidazolin-2-thion derivatives and process for their preparation | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1992-03-11 | — | — | EP | claimed |
| US-5162359-A | ANTIHYPERLIPOPROTEINEMIC 5-BENZYL SUBSTITUTED-BENZIMIDAZOLINE-2-THION DERIVATIVES | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1992-11-10 | — | — | US | disclosed |