Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 7/20 | 0.68 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12716519 | 0.90 | PSMB8 (0.59) | PSMB8KEAP1KDM4EALDH1A1GAA | |
| SCHEMBL8701312 | 0.87 | PSMB8 (0.62) | PSMB8KEAP1KDM4EALDH1A1GAA | |
| SCHEMBL8699552 | 0.84 | PSMB8 (0.68) | PSMB8KEAP1KDM4EALDH1A1GAA | |
| SCHEMBL8703483 | 0.84 | ALDH1A1 (0.52) | PSMB8KEAP1KDM4EALDH1A1GAA | |
| SCHEMBL31389040 | 0.81 | PSMB8 (1.00) | PSMB8KEAP1KDM4EALDH1A1GAA | |
| SCHEMBL799525 | 0.81 | PSMB8 (1.00) | PSMB8KEAP1KDM4EALDH1A1GAA | |
| SCHEMBL12716517 | 0.76 | PSMB8 (0.59) | PSMB8KEAP1KDM4EALDH1A1GAA | |
| SCHEMBL8700992 | 0.75 | PSMB8 (0.43) | PSMB8KEAP1KDM4EALDH1A1GAA | |
| SCHEMBL9660960 | 0.73 | MEN1 (0.79) | PSMB8KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL8697415 | 0.73 | PSMB8 (0.64) | PSMB8KEAP1KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998025913-A1 | NOVEL SUBSTITUTED 3H -BENZOXAZOLE-2-THIONES AND 3H -BENZOTHIAZOLE-2 THIONES DERIVATIVES, METHOD FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1998-06-18 | — | — | WO | disclosed |