Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 8/20 | 0.71 |
| ▸ | BLM | P54132 | 2/20 | 0.71 |
| ▸ | HBB | P68871 | 2/20 | 0.71 |
| ▸ | USP2 | O75604 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | EDNRA | P25101 | 1/20 | 0.71 |
| ▸ | HTR2A | P28223 | 1/20 | 0.71 |
| ▸ | RECQL | P46063 | 1/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.71 |
| ▸ | HPRT1 | P00492 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | VCP | P55072 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | POLG | P54098 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL9663155 | 0.99 | PNP (0.70) | PNPBLMHBBUSP2TSHR | |
| SCHEMBL17617332 | 0.88 | POLB (0.63) | PNPBLMHBBUSP2TSHR | |
| SCHEMBL29370760 | 0.87 | PNP (0.87) | PNPBLMHBBUSP2TSHR | |
| SCHEMBL97290 | 0.85 | PNP (0.72) | PNPBLMHBBUSP2TSHR | |
| SCHEMBL9662953 | 0.85 | PNP (0.69) | PNPBLMHBBUSP2TSHR | |
| SCHEMBL9662960 | 0.85 | PNP (0.69) | PNPBLMHBBUSP2TSHR | |
| SCHEMBL5443285 | 0.84 | PNP (0.74) | PNPBLMHBBUSP2TSHR | |
| SCHEMBL1767748 | 0.84 | PNP (0.74) | PNPBLMHBBUSP2TSHR | |
| SCHEMBL8842855 | 0.84 | PNP (0.74) | PNPBLMHBBUSP2TSHR | |
| Acyclovir SCHEMBL3664893 | 0.83 | PNP (1.00) | PNPBLMHBBUSP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0173624-B1 | 4-(GUANIN-9-YL) BUTANALS AND ANTIVIRAL COMPOSITIONS CONTAINING THEM | MERCK & CO. INC. (US) | 1992-04-08 | — | — | EP | claimed |
| US-4755516-A | Antiviral compounds | MERCK & CO., INC. (US) | 1988-07-05 | — | — | US | claimed |
| EP-0173624-A2 | 4-(guanin-9-yl) butanals and antiviral compositions containing them | MERCK & CO. INC. (US) | 1986-03-05 | — | — | EP | claimed |
| EP-2679584-B1 | CLATHRATE COMPLEX OF CYCLODEXTRIN OR ARABINOGALACTAN WITH 9-PHENYL-SYM-OCTAHYDROSELENOXANTHENE | PDSK LTD COMPANY L (RU) | 2016-08-03 | — | — | EP | disclosed |
| US-20140023713-A1 | CLATHRATE COMPLEX OF CYCLODEXTRIN OR ARABINOGALACTAN WITH 9-PHENYL-SYM-OCTA-HYDROSELENOXANTENE | TSYB ANATOLIY FEDOROVICH (RU) | 2014-01-23 | — | — | US | disclosed |
| EP-0173624-B1 | 4-(GUANIN-9-YL) BUTANALS AND ANTIVIRAL COMPOSITIONS CONTAINING THEM | MERCK & CO. INC. (US) | 1992-04-08 | — | — | EP | disclosed |
| US-4755516-A | Antiviral compounds | MERCK & CO., INC. (US) | 1988-07-05 | — | — | US | disclosed |
| EP-0173624-A2 | 4-(guanin-9-yl) butanals and antiviral compositions containing them | MERCK & CO. INC. (US) | 1986-03-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140023713-A1 | CLATHRATE COMPLEX OF CYCLODEXTRIN OR ARABINOGALACTAN WITH 9-PHENYL-SYM-OCTA-HYDROSELENOXANTENE | OSTC, SI, ABCG2 | PNP 896/4885BLM 3483/4885HBB 514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.