Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10753281 | 0.80 | ALDH1A1 (0.47) | ALDH1A1KDM4ESMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL659348 | 0.78 | ALDH1A1 (0.43) | ALDH1A1KDM4ESMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL293927 | 0.77 | ALDH1A1 (0.31) | ALDH1A1KDM4ESMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL12586735 | 0.77 | ALDH1A1 (0.45) | ALDH1A1KDM4ESMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL12767969 | 0.77 | ALDH1A1 (0.47) | ALDH1A1KDM4ESMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL10749843 | 0.77 | ALDH1A1 (0.53) | ALDH1A1KDM4ESMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL658570 | 0.76 | NPSR1 (0.49) | ALDH1A1KDM4ESMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL11337474 | 0.75 | HTR7 (0.56) | ALDH1A1KDM4ESMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL292606 | 0.75 | KMT2A (0.41) | ALDH1A1KDM4EL3MBTL1MAPTHTR1A | |
| SCHEMBL293027 | 0.74 | TSHR (0.53) | ALDH1A1KDM4ESMN1; SMN2POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5090994-A | HETEROCYCLIC COMPOUNDS AND HERBICIDAL COMPOSITIONS CONTAINING THE COMPOUNDS AS EFFECTIVE COMPONENTS | AGRO-KANESHO CO., LTD. (JP) | 1992-02-25 | — | — | US | disclosed |