SCHEMBL9664138

SCHEMBL9664138

[CH2]COc1ccc(OCC)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.74
TSHR P16473 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
LTA4H P09960 2/20 0.54
KDM4E B2RXH2 2/20 0.48
ALDH1A1 P00352 2/20 0.48
PARP10 Q53GL7 1/20 0.48
RELA Q04206 1/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
PRSS1 P07477 1/20 0.48
PRSS2 P07478 1/20 0.48
PRSS3 P35030 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
ADRA2A P08913 2/20 0.47
MAPT P10636 1/20 0.47
NPC1 O15118 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,4-Diethoxybenzene SCHEMBL27616183 0.86 NQO1 (0.88) NQO1TSHRTDP1LTA4HKDM4E
SCHEMBL4707838 0.86 NQO1 (0.47) NQO1TSHRTDP1LTA4HCA12
1,4-Diethoxybenzene SCHEMBL124015 0.86 NQO1 (1.00) NQO1TSHRTDP1LTA4HKDM4E
1,4-Diethoxybenzene SCHEMBL28186701 0.86 NQO1 (1.00) NQO1TSHRTDP1LTA4HKDM4E
1,4-Diethoxybenzene SCHEMBL11794798 0.83 NQO1 (0.93) NQO1TSHRTDP1LTA4HKDM4E
SCHEMBL9208516 0.81 TP53 (0.59) NQO1TSHRTDP1LTA4HKDM4E
SCHEMBL3138590 0.80 SMN1; SMN2 (0.48) NQO1TDP1ALDH1A1SMN1; SMN2MAPT
SCHEMBL5492634 0.80 LTA4H (0.57) TSHRLTA4HCA12CA1CA2
SCHEMBL58858 0.80 NQO1 (0.67) NQO1TSHRTDP1LTA4HKDM4E
SCHEMBL11042247 0.80 NQO1 (0.67) NQO1TSHRTDP1LTA4HKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5090994-A HETEROCYCLIC COMPOUNDS AND HERBICIDAL COMPOSITIONS CONTAINING THE COMPOUNDS AS EFFECTIVE COMPONENTS AGRO-KANESHO CO., LTD. (JP) 1992-02-25 US disclosed
CN-1045263-A Heterogeneous ring compound prepares their method, and contains the herbicidal composition of this compounds as effective constituent AGRO KANESHO CO LTD (JP) 1990-09-12 CN disclosed