Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 5/20 | 0.51 |
| ▸ | NOD2 | Q9HC29 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10002626 | 0.75 | NOD1 (0.61) | NOD1NOD2MAPTKDM4ELMNA | |
| SCHEMBL10003206 | 0.74 | NOD1 (0.58) | NOD1NOD2MAPTKDM4ELMNA | |
| SCHEMBL14627380 | 0.74 | NOD1 (0.78) | NOD1NOD2MAPTLMNAALDH1A1 | |
| SCHEMBL30889670 | 0.73 | NOD1 (0.53) | NOD1NOD2MAPTKDM4ELMNA | |
| SCHEMBL10003163 | 0.73 | NOD1 (0.53) | NOD1NOD2MAPTKDM4ELMNA | |
| SCHEMBL30889582 | 0.73 | NOD1 (0.53) | NOD1NOD2MAPTKDM4ELMNA | |
| SCHEMBL10003676 | 0.73 | NOD1 (0.56) | NOD1NOD2MAPTKDM4ELMNA | |
| SCHEMBL3186556 | 0.72 | CYP2C9 (0.51) | MAPTKDM4ELMNATSHRALDH1A1 | |
| SCHEMBL23147960 | 0.72 | NOD2 (0.44) | NOD1NOD2MAPTKDM4ELMNA | |
| SCHEMBL29812861 | 0.72 | NOD2 (0.44) | NOD1NOD2MAPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511791-A2 | Pyrrolopyridine derivatives as Angiotensin inhibitors | ZENECA LIMITED (GB) | 1992-11-04 | — | — | EP | disclosed |