SCHEMBL9664391

SCHEMBL9664391

O=C1C2CCCCN2C(=O)N1c1cc(O)c(Cl)cc1F

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
AR P10275 2/20 0.45
PPOX P50336 4/20 0.42
POLB P06746 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.36
LMNA P02545 1/20 0.36
ALDH1A1 P00352 2/20 0.35
HPGD P15428 1/20 0.35
KMT2A Q03164 1/20 0.34
HSP90AA1 P07900 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10440318 0.85 AR (0.45) ARPPOXPOLBSMN1; SMN2LMNA
SCHEMBL10935874 0.85 AR (0.45) ARPPOXSMN1; SMN2LMNAALDH1A1
SCHEMBL31448212 0.85 AR (0.42) ARPPOXPOLBSMN1; SMN2LMNA
SCHEMBL10823806 0.84 HPGD (0.42) ARPPOXPOLBSMN1; SMN2HPGD
SCHEMBL9382971 0.82 AR (0.42) ARSMN1; SMN2ALDH1A1HPGD
SCHEMBL10613566 0.82 PPOX (0.65) ARPPOXPOLBSMN1; SMN2LMNA
SCHEMBL8685948 0.81 PPOX (0.53) ARPPOXPOLBKMT2A
SCHEMBL10931755 0.81 AR (0.53) ARPPOXPOLBSMN1; SMN2LMNA
SCHEMBL11038098 0.80 AR (0.52) ARPPOXPOLBSMN1; SMN2LMNA
SCHEMBL10939313 0.80 PPOX (0.54) ARPPOXPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119613398-A Tetra-substituted phenyl ether (thioether) compound containing alkoxy acetate substituent and application thereof 江西天宇化工有限公司 2025-03-14 CN disclosed
US-5090994-A HETEROCYCLIC COMPOUNDS AND HERBICIDAL COMPOSITIONS CONTAINING THE COMPOUNDS AS EFFECTIVE COMPONENTS AGRO-KANESHO CO., LTD. (JP) 1992-02-25 US disclosed