Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.58 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | PTGES | O14684 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5466784 | 0.93 | KDM4E (0.62) | KDM4ELMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL9210387 | 0.82 | KDM4E (0.64) | KDM4ESOAT1LMNAHPGD | |
| SCHEMBL9215059 | 0.82 | KDM4E (0.64) | KDM4ELMNAHPGDPTGES | |
| SCHEMBL9375339 | 0.82 | SOAT2 (0.57) | SOAT2SOAT1 | |
| SCHEMBL5481419 | 0.81 | PTGS1 (0.54) | KDM4ELMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL9370118 | 0.81 | SOAT2 (0.58) | SOAT2SOAT1 | |
| SCHEMBL9370785 | 0.81 | SOAT2 (0.58) | SOAT2SOAT1 | |
| SCHEMBL9217701 | 0.80 | ACAT1 (0.66) | KDM4ESOAT1 | |
| SCHEMBL9212895 | 0.80 | ACAT1 (0.66) | KDM4ESOAT1 | |
| SCHEMBL9213347 | 0.80 | ACAT1 (0.66) | KDM4ESOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519996-A1 | IMIDAZOLES | RHONE-POULENC RORER LIMITED (GB) | 1992-12-30 | — | — | EP | disclosed |
| WO-1991013876-A1 | IMIDAZOLES | RHONE-POULENC RORER LIMITED (GB) | 1991-09-19 | — | — | WO | disclosed |