Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | RARA | P10276 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.41 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 4/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9664301 | 0.92 | RARB (0.47) | MAOBRARARARBLMNAL3MBTL1 | |
| SCHEMBL9664333 | 0.89 | MAOB (0.53) | MAOBRARARARBTAAR1 | |
| SCHEMBL9662872 | 0.86 | MAOB (0.53) | MAOBMCHR1L3MBTL1HTTTAAR1 | |
| SCHEMBL9664339 | 0.85 | RARB (0.53) | MAOBRARARARBL3MBTL1TAAR1 | |
| SCHEMBL9664957 | 0.84 | RARB (0.55) | MAOBRARARARBLMNATSHR | |
| SCHEMBL9664866 | 0.82 | MAOB (0.45) | MAOBMCHR1RARBLMNAL3MBTL1 | |
| SCHEMBL9664954 | 0.80 | RARB (0.47) | MAOBRARARARBSMN1; SMN2TAAR1 | |
| SCHEMBL7858113 | 0.80 | CYP17A1 (0.46) | — | |
| SCHEMBL14766929 | 0.79 | S1PR1 (0.47) | MAOBRARARARBLMNAL3MBTL1 | |
| SCHEMBL8990702 | 0.78 | PTPN7 (0.54) | MAOBLMNAL3MBTL1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093026-A | Liquid crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-03-03 | — | — | US | disclosed |
| WO-1990008756-A1 | DIPHENYLETHANES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-08-09 | — | — | WO | disclosed |