Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9665388 | 0.81 | HCRTR1 (0.49) | MEN1KMT2AKDM4ENPC1TP53 | |
| SCHEMBL9665564 | 0.80 | CYP19A1 (0.47) | KDM4ENPC1RAB9APPARDALDH1A1 | |
| SCHEMBL9664437 | 0.80 | MAPT (0.43) | MEN1KMT2AKDM4EHSD17B10PPARD | |
| Hydrochloric Acid SCHEMBL9452000 | 0.79 | LMNA (0.50) | MEN1KMT2AKDM4ENPC1TP53 | |
| Hydrochloric Acid SCHEMBL9451978 | 0.78 | GAA (0.56) | MEN1KMT2AKDM4ENPC1TP53 | |
| SCHEMBL9665771 | 0.77 | PPARD (0.49) | MEN1KMT2AKDM4EPPARDALDH1A1 | |
| SCHEMBL7621279 | 0.76 | MAPK14 (0.51) | KDM4ENPC1RAB9APPARDALDH1A1 | |
| SCHEMBL9666106 | 0.76 | MAPT (0.46) | MEN1KMT2AKDM4EPPARDALDH1A1 | |
| SCHEMBL9665398 | 0.76 | MAPK14 (0.48) | MEN1KMT2AKDM4ENPC1TP53 | |
| SCHEMBL9666206 | 0.75 | CYP19A1 (0.49) | MEN1KMT2AKDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0149884-B1 | 5-PYRIDYL-1,3-THIAZOLE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1992-12-16 | — | — | EP | disclosed |
| US-4612321-A | 5-pyridyl-1,3-thiazole derivatives | TAKEDA CHEMICAL INDUSTRIES, INC. (JP) | 1986-09-16 | — | — | US | disclosed |
| EP-0149884-A2 | 5-Pyridyl-1,3-thiazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1985-07-31 | — | — | EP | disclosed |