Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | AHR | P35869 | 1/20 | 0.56 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | HTR1D | P28221 | 1/20 | 0.50 |
| ▸ | HTR1B | P28222 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12949464 | 0.83 | HTR2A (0.56) | MEN1KMT2AMAPTCYP3A4AHR | |
| SCHEMBL2940909 | 0.83 | MEN1 (0.56) | MEN1KMT2AMAPTCYP3A4AHR | |
| SCHEMBL28224556 | 0.77 | MEN1 (0.62) | MEN1KMT2AMAPTCYP3A4AHR | |
| SCHEMBL347688 | 0.77 | MEN1 (0.62) | MEN1KMT2AMAPTCYP3A4AHR | |
| SCHEMBL431743 | 0.75 | CYP3A4 (0.35) | CYP3A4ALDH1A1HPGD | |
| SCHEMBL29386855 | 0.75 | CYP3A4 (0.35) | CYP3A4ALDH1A1HPGD | |
| SCHEMBL348936 | 0.74 | HTR2A (0.61) | MEN1KMT2AMAPTCYP3A4AHR | |
| SCHEMBL6524121 | 0.74 | MEN1 (0.69) | MEN1KMT2AMAPTCYP3A4AHR | |
| SCHEMBL29413080 | 0.74 | MEN1 (0.69) | MEN1KMT2AMAPTCYP3A4AHR | |
| SCHEMBL90504 | 0.74 | MEN1 (0.69) | MEN1KMT2AMAPTCYP3A4AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240352-B1 | 5-FLUOROURACIL DERIVATIVES AND PROCESSES FOR PRODUCING THEREOF | Chisso Corporation (JP) | 1992-12-16 | — | — | EP | disclosed |
| US-4792607-A | ANTICANCER MEDICINE INTERRMEDIATES | CHISSO CORPORATION (JP) | 1988-12-20 | — | — | US | disclosed |
| EP-0240352-A2 | 5-Fluorouracil derivatives and processes for producing thereof | Chisso Corporation (JP) | 1987-10-07 | — | — | EP | disclosed |