Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 9/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 7/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9663411 | 0.99 | AGTR1 (0.39) | AGTR1AGTR2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9662370 | 0.89 | GP6 (0.39) | AGTR1AGTR2CYP3A4CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL9664091 | 0.89 | GP6 (0.39) | AGTR1AGTR2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9662968 | 0.85 | AGTR1 (0.38) | AGTR1AGTR2CYP3A4CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL9664337 | 0.84 | AGTR1 (0.37) | AGTR1AGTR2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9664871 | 0.84 | AGTR1 (0.35) | AGTR1AGTR2 | |
| Hydrochloric Acid SCHEMBL9350416 | 0.81 | AGTR1 (0.43) | AGTR1AGTR2CYP3A4CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL9346785 | 0.81 | AGTR1 (0.42) | AGTR1AGTR2CYP3A4CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL9346934 | 0.81 | AGTR1 (0.43) | AGTR1AGTR2CYP3A4CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL9350405 | 0.81 | AGTR1 (0.44) | AGTR1AGTR2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511791-A2 | Pyrrolopyridine derivatives as Angiotensin inhibitors | ZENECA LIMITED (GB) | 1992-11-04 | — | — | EP | claimed |