Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | NPC1 | O15118 | 2/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | STS | P08842 | 7/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | ESR1 | P03372 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.62 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8197525 | 1.00 | MAPT (0.66) | MAPTALDH1A1NPC1RAB9ASTS | |
| SCHEMBL9650912 | 0.97 | MAPT (0.67) | MAPTALDH1A1NPC1RAB9ASTS | |
| SCHEMBL516632 | 0.95 | ESR1 (0.68) | MAPTALDH1A1NPC1RAB9ASTS | |
| SCHEMBL9446681 | 0.94 | LMNA (0.56) | MAPTALDH1A1NPC1RAB9ASTS | |
| SCHEMBL9446645 | 0.92 | LMNA (0.57) | MAPTALDH1A1NPC1RAB9ASTS | |
| SCHEMBL15165085 | 0.92 | MAPT (0.57) | MAPTALDH1A1NPC1RAB9ASTS | |
| SCHEMBL10423327 | 0.91 | LMNA (0.62) | MAPTALDH1A1NPC1RAB9ASTS | |
| SCHEMBL19373812 | 0.91 | MAPT (0.74) | MAPTALDH1A1NPC1RAB9ASTS | |
| SCHEMBL10344104 | 0.91 | MAPT (0.74) | MAPTALDH1A1NPC1RAB9ASTS | |
| SCHEMBL19373809 | 0.91 | MAPT (0.74) | MAPTALDH1A1NPC1RAB9ASTS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0313379-B1 | OPTICALLY ACTIVE COMPOUND HAVING DELTA-VALEROLACTONE RING AND LIQUID CRYSTAL COMPOSITION COMPRISING SAME | MITSUBISHI RAYON CO., LTD. (JP) | 1992-07-22 | — | — | EP | disclosed |
| US-5045228-A | Useful for high speed print heads | MITSUBISHI RAYON COMPANY LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0313379-A2 | Optically active compound having delta-valerolactone ring and liquid crystal composition comprising same | MITSUBISHI RAYON CO., LTD. (JP) | 1989-04-26 | — | — | EP | disclosed |