Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.68 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | STS | P08842 | 7/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8197525 | 0.95 | MAPT (0.66) | ESR1LMNACYP1A2TSHRCYP2C19 | |
| SCHEMBL9664878 | 0.95 | MAPT (0.66) | ESR1LMNACYP1A2TSHRCYP2C19 | |
| SCHEMBL10423327 | 0.95 | LMNA (0.62) | ESR1LMNACYP1A2TSHRCYP2C19 | |
| SCHEMBL9446645 | 0.93 | LMNA (0.57) | ESR1LMNACYP1A2TSHRCYP2C19 | |
| SCHEMBL9650912 | 0.93 | MAPT (0.67) | ESR1LMNACYP1A2TSHRCYP2C19 | |
| SCHEMBL4644691 | 0.92 | ALDH1A1 (0.64) | ESR1LMNACYP1A2TSHRCYP2C19 | |
| SCHEMBL9446681 | 0.92 | LMNA (0.56) | ESR1LMNACYP1A2TSHRCYP2C19 | |
| SCHEMBL7123794 | 0.90 | LMNA (0.68) | ESR1LMNACYP1A2TSHRCYP2C19 | |
| SCHEMBL10344348 | 0.90 | LMNA (0.72) | ESR1LMNACYP1A2TSHRCYP2C19 | |
| SCHEMBL20987320 | 0.89 | MAPT (0.63) | ESR1LMNACYP1A2TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2473606-B1 | Controlling transgene expression across the skin | ETH ZUERICH (CH) | 2016-06-29 | — | — | EP | disclosed |
| US-8653046-B2 | Controlling transgene expression across the skin | ETH ZURICH (CH) | 2014-02-18 | — | — | US | disclosed |
| EP-2473606-A1 | CONTROLLING TRANSGENE EXPRESSION ACROSS THE SKIN | ETH Zurich (CH) | 2012-07-11 | — | — | EP | disclosed |
| US-20120029074-A1 | CONTROLLING TRANSGENE EXPRESSION ACROSS THE SKIN | ETH ZURICH (CH) | 2012-02-02 | — | — | US | disclosed |
| WO-2010115583-A1 | CONTROLLING TRANSGENE EXPRESSION ACROSS THE SKIN | ETH ZURICH (CH) | 2010-10-14 | — | — | WO | disclosed |
| EP-2239326-A1 | Controlling transgene expression across the skin | ETH Zurich (CH) | 2010-10-13 | — | — | EP | disclosed |
| EP-0342652-B1 | Thermoplastic wholly aromatic copolyimide ester and process for producing the same | IDEMITSU PETROCHEMICAL CO (JP) | 1995-03-08 | — | — | EP | disclosed |
| US-5003030-A | Thermoplastic wholly aromatic copolyimide ester and process for producing the same | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 1991-03-26 | — | — | US | disclosed |
| EP-0342652-A2 | Thermoplastic wholly aromatic copolyimide ester and process for producing the same | IDEMITSU PETROCHEMICAL CO. LTD. (JP) | 1989-11-23 | — | — | EP | disclosed |
| US-3962314-A | Oxybenzoyl dioxyarylene mono- and diesters | THE CARBORUNDUM COMPANY (US) | 1976-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120029074-A1 | CONTROLLING TRANSGENE EXPRESSION ACROSS THE SKIN | REL, CUTA, PTAR1 | ESR1 2343/4885LMNA 3576/4885CYP1A2 4410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.