Sugi Predict

Sugi Predict / Compounds / SCHEMBL966496

SCHEMBL966496

SCHEMBL966496

CCOC(=O)CC(=O)c1cc(F)c(F)c(OC)c1F

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.54
▸ MEN1 O00255 2/20 0.54
▸ KMT2A Q03164 2/20 0.54
▸ KDM4E B2RXH2 1/20 0.54
▸ GAA P10253 2/20 0.39
▸ MGAM O43451 1/20 0.39
▸ SI P14410 1/20 0.39
▸ MGAM2 Q2M2H8 1/20 0.39
▸ MIF P14174 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ NLRP3 Q96P20 1/20 0.36
▸ MAPT P10636 3/20 0.35
▸ LMNA P02545 1/20 0.35
▸ MAPK1 P28482 1/20 0.35
▸ CASP1 P29466 1/20 0.35
▸ CASP7 P55210 1/20 0.35
▸ HTT P42858 1/20 0.34
▸ TNF P01375 1/20 0.34
▸ HSD17B1 P14061 1/20 0.34
▸ HSD17B2 P37059 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30181119 1.00 ALDH1A1 (0.54) ALDH1A1MEN1KMT2AKDM4EGAA
SCHEMBL9266273 0.88 MEN1 (0.50) ALDH1A1MEN1KMT2AKDM4EGAA
SCHEMBL6239436 0.88 ALDH1A1 (0.50) ALDH1A1MEN1KMT2AKDM4EGAA
SCHEMBL3197468 0.87 ALDH1A1 (0.43) ALDH1A1MEN1KMT2AKDM4EGAA
SCHEMBL26690754 0.86 ALDH1A1 (0.42) ALDH1A1MEN1KMT2AKDM4EGAA
SCHEMBL1185918 0.85 ALDH1A1 (0.44) ALDH1A1MEN1KMT2AKDM4EGAA
SCHEMBL30958584 0.85 ALDH1A1 (0.44) ALDH1A1MEN1KMT2AKDM4EGAA
SCHEMBL7005401 0.85 ALDH1A1 (0.41) ALDH1A1MEN1KMT2AKDM4EGAA
SCHEMBL7811132 0.85 ALDH1A1 (0.41) ALDH1A1MEN1KMT2AKDM4EGAA
SCHEMBL3190037 0.84 ALDH1A1 (0.43) ALDH1A1MEN1KMT2AKDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240254136-A1 COMPOUNDS TARGETING RNA-BINDING PROTEINS OR RNA-MODIFYING PROTEINS Redona Therapeutics, Inc. 2024-08-01 — — US disclosed
WO-2024138292-A1 NOVEL PHENYLQUINOLONE COMPOUND HAVING ANTIBACTERIAL AND ANTICANCER FUNCTIONS, AND PREPARATION THEREOF 深圳阿尔法分子科技有限责任公司 2024-07-04 — — WO disclosed
WO-2024138292-A1 NOVEL PHENYLQUINOLONE COMPOUND HAVING ANTIBACTERIAL AND ANTICANCER FUNCTIONS, AND PREPARATION THEREOF 深圳阿尔法分子科技有限责任公司 2024-07-04 — — WO disclosed
WO-2024141126-A1 NEW PHENYLQUINOLONE COMPOUND HAVING ANTIBACTERIAL AND ANTI-CANCER FUNCTIONS AND PREPARATION THEREOF 深圳阿尔法分子科技有限责任公司 2024-07-04 — — WO disclosed
CN-118255716-A Novel phenyl quinolone compound with antibacterial and anticancer functions and preparation thereof 深圳阿尔法分子科技有限责任公司 2024-06-28 — — CN disclosed
CN-116157392-A Compounds targeting RNA binding proteins or RNA modification proteins 雷多纳治疗公司 2023-05-23 — — CN disclosed
EP-4114831-A1 COMPOUNDS TARGETING RNA-BINDING PROTEINS OR RNA-MODIFYING PROTEINS Twentyeight-Seven, Inc. (US) 2023-01-11 — — EP disclosed
EP-2998304-B1 METHOD FOR PRODUCING (1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO-8-METHOXY-7-[(4AS,7AS)-OCTAHYDRO-6H-PYRROLO[3,4-B]PYRIDIN-6-YL]-4-OXO-3-QUINOLINE-CARBOXYLIC ACID DERKACH NATALIIA MYKOLAIVNA (UA) 2017-08-30 — — EP disclosed
EP-2998304-B1 METHOD FOR PRODUCING (1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO-8-METHOXY-7-[(4AS,7AS)-OCTAHYDRO-6H-PYRROLO[3,4-B]PYRIDIN-6-YL]-4-OXO-3-QUINOLINE-CARBOXYLIC ACID DERKACH NATALIIA MYKOLAIVNA (UA) 2017-08-30 — — EP disclosed
CN-104507938-B Preparation method of 1-cyclopropyl-7- (S, S-2, 8-diazo-bicyclo [4.3.0] nonane-8-yl) -6-fluoro-8-methoxy-1, 4-dihydro-4-oxo-3-quinoline carboxylic acid 娜塔莉亚·米克拉维娜·德卡奇 2017-02-15 — — CN disclosed
WO-1996001262-A1 NOVEL QUINOLINE COMPOUND AND PROCESS FOR PREPARATION THEREOF HANMI PHARMACEUTICAL CO., LTD. (KR) 1996-01-18 — — WO disclosed
US-5393758-A Bactericides, microbiocides LABORATORIOS DEL DR. ESTEVE S.A. (ES) 1995-02-28 — — US disclosed
US-5385913-A 1,4-dihydro-4-oxo-3-quinoline derivatives as selectively toxic mammalian antibacterial agents PFIZER INC. (US) 1995-01-31 — — US disclosed
EP-0421668-B1 1,4-Dihydro-4-oxo-3-quinolone derivatives as selectively toxic mammalian antibacterial agents PFIZER (US) 1995-01-04 — — EP disclosed
EP-0230295-B1 8-alkoxyquinolonecarboxylic acid and salts thereof excellent in the selective toxicity and process of preparing the same KYORIN SEIYAKU KK (JP) 1994-05-25 — — EP disclosed
US-5043450-A Bactericides KYORIN PHARMACEUTICAL CO., LTD. (JP) 1991-08-27 — — US disclosed
WO-1991004972-A1 1,4-DIHYDRO-4-OXO-3-QUINOLINE DERIVATIVES AS SELECTIVELY TOXIC MAMMALIAN ANTIBACTERIAL AGENTS PFIZER INC. (US) 1991-04-18 — — WO disclosed
EP-0421668-A2 1,4-Dihydro-4-oxo-3-quinolone derivatives as selectively toxic mammalian antibacterial agents PFIZER INC. (US) 1991-04-10 — — EP disclosed
US-4980470-A 8-alkoxyquinolonecarboxylic acid and salts thereof KYORIN PHARMACEUTICAL CO., LTD. (JP) 1990-12-25 — — US disclosed
EP-0230295-A2 8-alkoxyquinolonecarboxylic acid and salts thereof excellent in the selective toxicity and process of preparing the same KYORIN PHARMACEUTICAL CO., LTD. (JP) 1987-07-29 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240254136-A1 COMPOUNDS TARGETING RNA-BINDING PROTEINS OR RNA-MODIFYING PROTEINS NSUN3, NSUN2, RBM3 ALDH1A1 3491/4885MEN1 2158/4885KMT2A 1035/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.