Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7811132 | 0.90 | ALDH1A1 (0.41) | ALDH1A1KDM4EMEN1KMT2AMIF | |
| SCHEMBL966496 | 0.85 | ALDH1A1 (0.54) | ALDH1A1KDM4EMEN1KMT2AMIF | |
| SCHEMBL30181119 | 0.85 | ALDH1A1 (0.54) | ALDH1A1KDM4EMEN1KMT2AMIF | |
| SCHEMBL3197468 | 0.84 | ALDH1A1 (0.43) | ALDH1A1KDM4EMEN1KMT2AMIF | |
| SCHEMBL1185918 | 0.82 | ALDH1A1 (0.44) | ALDH1A1KDM4EMEN1KMT2AMIF | |
| SCHEMBL30958584 | 0.82 | ALDH1A1 (0.44) | ALDH1A1KDM4EMEN1KMT2AMIF | |
| SCHEMBL3190037 | 0.80 | ALDH1A1 (0.43) | ALDH1A1KDM4EMEN1KMT2AMIF | |
| SCHEMBL5523919 | 0.80 | ALDH1A1 (0.39) | ALDH1A1KDM4EMEN1KMT2AMIF | |
| SCHEMBL7007708 | 0.79 | ALDH1A1 (0.39) | ALDH1A1KDM4EMEN1KMT2AMIF | |
| Acetic Acid SCHEMBL8870017 | 0.78 | ALDH1A1 (0.41) | ALDH1A1KDM4EMEN1KMT2AMIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945435-B1 | NOVEL PYRIDONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | WAKUNAGA PHARMA CO LTD (JP) | 2003-08-13 | — | — | EP | disclosed |
| US-6136823-A | BACTERICIDES OR VIRICIDES | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0945435-A1 | NOVEL PYRIDONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |