Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.77 |
| ▸ | PTGES | O14684 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 5/20 | 0.69 |
| ▸ | HPGD | P15428 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | CNR1 | P21554 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7815045 | 0.88 | KDM4E (0.97) | KDM4EPTGESMAPTHPGDLMNA | |
| SCHEMBL11418640 | 0.84 | MAPK14 (0.56) | KDM4EPTGESMAPTHPGDLMNA | |
| SCHEMBL9425483 | 0.81 | KDM4E (0.69) | KDM4EPTGESMAPTHPGDLMNA | |
| SCHEMBL9375771 | 0.81 | KDM4E (0.74) | KDM4EPTGESMAPTHPGDLMNA | |
| SCHEMBL9663829 | 0.80 | PTGS1 (0.75) | KDM4EPTGESMAPTHPGDLMNA | |
| SCHEMBL5466784 | 0.80 | KDM4E (0.62) | KDM4EPTGESMAPTHPGDLMNA | |
| SCHEMBL13516893 | 0.80 | KDM4E (0.72) | KDM4EPTGESMAPTHPGDLMNA | |
| SCHEMBL9215071 | 0.80 | KDM4E (0.68) | KDM4EPTGESHPGDLMNAALDH1A1 | |
| SCHEMBL9664403 | 0.78 | KDM4E (0.60) | KDM4EPTGESMAPTHPGDLMNA | |
| SCHEMBL3174806 | 0.78 | KDM4E (0.65) | KDM4EPTGESMAPTHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519996-A1 | IMIDAZOLES | RHONE-POULENC RORER LIMITED (GB) | 1992-12-30 | — | — | EP | disclosed |
| WO-1991013876-A1 | IMIDAZOLES | RHONE-POULENC RORER LIMITED (GB) | 1991-09-19 | — | — | WO | disclosed |