Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.56 |
| ▸ | CTSK | P43235 | 1/20 | 0.56 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | CPA1 | P15085 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | VNN1 | O95497 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27563011 | 0.87 | CTSS (0.57) | CTSSCTSKCTNNB1CYP3A4MME | |
| SCHEMBL6318009 | 0.87 | CTSS (0.57) | CTSSCTSKCTNNB1CYP3A4MME | |
| SCHEMBL9740320 | 0.79 | CTSS (0.51) | CTSSCTSKCTNNB1CYP3A4MME | |
| SCHEMBL9668155 | 0.78 | CTNNB1 (0.52) | CTSSCTSKCTNNB1MMEACE | |
| SCHEMBL10389693 | 0.78 | CTNNB1 (0.52) | CTSSCTSKCTNNB1MMEACE | |
| SCHEMBL9668142 | 0.78 | CTNNB1 (0.52) | CTSSCTSKCTNNB1MMEACE | |
| SCHEMBL9665156 | 0.77 | CTNNB1 (0.51) | CTSSCTSKCTNNB1CYP3A4MME | |
| SCHEMBL613640 | 0.77 | CTSS (0.76) | CTSSCTSKCYP3A4MMEACE | |
| SCHEMBL4600435 | 0.77 | CTSS (0.76) | CTSSCTSKCYP3A4MMEACE | |
| SCHEMBL4122289 | 0.77 | CTSS (0.76) | CTSSCTSKCYP3A4MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0184550-B1 | 5-AMINO-4-HYDROXY VALERYL AMIDE DERIVATIVES | CIBA-GEIGY AG (CH) | 1992-03-18 | — | — | EP | disclosed |
| US-4931591-A | Novel 5-amino-4-hydroxyvaleryl derivatives | CIBA-GEIGY CORPORATION (US) | 1990-06-05 | — | — | US | disclosed |
| US-4727060-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1988-02-23 | — | — | US | disclosed |
| EP-0184550-A2 | 5-Amino-4-hydroxy valeryl amide derivatives | CIBA-GEIGY AG (CH) | 1986-06-11 | — | — | EP | disclosed |