Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | BLM | P54132 | 2/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | CAD | P27708 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9662670 | 0.83 | HTT (0.57) | HTTKMT2AITGA4 | |
| SCHEMBL2333909 | 0.82 | HTT (1.00) | HTTKMT2AMAPTMAPK1MEN1 | |
| SCHEMBL9664010 | 0.82 | KMT2A (0.72) | HTTKMT2ATSHRCYP1A2 | |
| SCHEMBL9487701 | 0.72 | HTT (0.70) | HTTKMT2AITGA4MAPTMEN1 | |
| SCHEMBL10949228 | 0.72 | HTT (0.70) | HTTKMT2AITGA4MAPTMEN1 | |
| SCHEMBL13439524 | 0.72 | HTT (0.42) | HTTKMT2AMAPTMEN1GAA | |
| SCHEMBL29544906 | 0.69 | HTT (0.59) | HTTKMT2AITGA4 | |
| SCHEMBL1973599 | 0.68 | HTT (0.55) | HTTKMT2AITGA4MAPTMEN1 | |
| SCHEMBL5550440 | 0.68 | HTT (0.55) | HTTKMT2AITGA4MAPTMEN1 | |
| SCHEMBL9662640 | 0.67 | KMT2A (0.60) | HTTKMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128467-A | Immunomodulation, liver disorders | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1992-07-07 | — | — | US | disclosed |
| US-5082836-A | Autoimmune diseases | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1992-01-21 | — | — | US | disclosed |
| US-5041435-A | Treatment of Liver Disorders and Autoimmune Diseases | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1991-08-20 | — | — | US | disclosed |
| EP-0356006-A1 | Cyclic sulfur-containing compounds | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1990-02-28 | — | — | EP | disclosed |