Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.46 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | FABP6 | P51161 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9665274 | 0.92 | SMN1; SMN2 (0.55) | RAB9ANPC1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9668106 | 0.89 | NPC1 (0.44) | RAB9ANPC1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9665163 | 0.87 | RAB9A (0.44) | RAB9ANPC1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9665287 | 0.87 | RAB9A (0.62) | RAB9ANPC1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9667320 | 0.84 | SMN1; SMN2 (0.48) | RAB9ANPC1LMNASMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9665997 | 0.84 | SMN1; SMN2 (0.48) | RAB9ANPC1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9665330 | 0.82 | RAB9A (0.52) | RAB9ANPC1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9665317 | 0.82 | RAB9A (0.44) | RAB9ANPC1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL10684439 | 0.81 | NPC1 (0.43) | RAB9ANPC1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9665290 | 0.81 | RAB9A (0.69) | RAB9ANPC1LMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234980-B1 | 2-BENZIMIDAZOLYLALKYLTHIO (OR SULFINYL OR SULFONYL) DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1992-09-16 | — | — | EP | claimed |