Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.69 |
| ▸ | NPC1 | O15118 | 6/20 | 0.69 |
| ▸ | LMNA | P02545 | 5/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9665339 | 0.88 | KMT2A (0.56) | RAB9ANPC1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9665330 | 0.88 | RAB9A (0.52) | RAB9ANPC1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9665730 | 0.84 | KMT2A (0.49) | RAB9ANPC1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9667087 | 0.84 | NPC1 (0.48) | RAB9ANPC1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9667096 | 0.84 | KMT2A (0.52) | RAB9ANPC1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL600508 | 0.82 | NPC1 (1.00) | RAB9ANPC1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9665254 | 0.82 | NPC1 (0.46) | RAB9ANPC1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9665257 | 0.82 | CYP2E1 (0.52) | RAB9ANPC1LMNACYP1A2CYP3A4 | |
| SCHEMBL9665274 | 0.81 | SMN1; SMN2 (0.55) | RAB9ANPC1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9665262 | 0.81 | RAB9A (0.46) | RAB9ANPC1LMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234980-B1 | 2-BENZIMIDAZOLYLALKYLTHIO (OR SULFINYL OR SULFONYL) DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1992-09-16 | — | — | EP | claimed |