Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.58 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.58 |
| ▸ | FEN1 | P39748 | 1/20 | 0.58 |
| ▸ | KDR | P35968 | 11/20 | 0.47 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | QPCT | Q16769 | 1/20 | 0.40 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8830055 | 0.81 | LOXL2 (0.58) | LOXL2ERCC5FEN1KDRLOXL3 | |
| SCHEMBL21812622 | 0.81 | LOXL2 (0.84) | LOXL2ERCC5FEN1KDRLOXL3 | |
| SCHEMBL28207097 | 0.81 | LOXL2 (0.58) | LOXL2ERCC5FEN1KDRLOXL3 | |
| SCHEMBL17014778 | 0.81 | LOXL2 (0.58) | LOXL2ERCC5FEN1KDRLOXL3 | |
| SCHEMBL2226003 | 0.81 | ERCC5 (0.63) | LOXL2ERCC5FEN1KDRLOXL3 | |
| SCHEMBL2226631 | 0.81 | LOXL2 (0.58) | LOXL2ERCC5FEN1KDRLOXL3 | |
| SCHEMBL330645 | 0.79 | LOXL2 (0.57) | LOXL2ERCC5FEN1KDRLOXL3 | |
| SCHEMBL28815683 | 0.78 | LOXL2 (0.55) | LOXL2ERCC5FEN1KDRLOXL3 | |
| SCHEMBL2227416 | 0.78 | LOXL2 (0.64) | LOXL2ERCC5FEN1KDRLOXL3 | |
| SCHEMBL5153800 | 0.78 | ERCC5 (0.54) | LOXL2ERCC5FEN1KDRHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0209751-B1 | CEPHALOSPORIN DERIVATIVES AND BACTERICIDES CONTAINING THE SAME | MEIJI SEIKA KAISHA LTD. (JP) | 1992-09-16 | — | — | EP | disclosed |
| EP-0209751-A2 | Cephalosporin derivatives and bactericides containing the same | MEIJI SEIKA KAISHA LTD. (JP) | 1987-01-28 | — | — | EP | disclosed |