Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 5/20 | 0.48 |
| ▸ | HTR2A | P28223 | 3/20 | 0.48 |
| ▸ | HTR2B | P41595 | 3/20 | 0.48 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9665683 | 0.80 | PDE1C (0.47) | ALDH1A1GAAMAPTHTR2CHTR2A | |
| SCHEMBL6926221 | 0.74 | PDE1C (0.47) | ALDH1A1GAAMAPTHTR2CHTR2A | |
| SCHEMBL6926219 | 0.74 | PDE1C (0.47) | ALDH1A1GAAMAPTHTR2CHTR2A | |
| SCHEMBL874954 | 0.71 | KDM1A (0.53) | — | |
| SCHEMBL21066065 | 0.71 | KDM1A (0.53) | — | |
| SCHEMBL2766130 | 0.71 | KDM1A (0.53) | — | |
| SCHEMBL8041609 | 0.71 | KDM1A (0.53) | — | |
| SCHEMBL21066062 | 0.71 | KDM1A (0.53) | — | |
| SCHEMBL4739718 | 0.71 | KDM1A (0.53) | — | |
| Hydrochloric Acid SCHEMBL2073275 | 0.70 | KDM1A (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0135429-B1 | THE SYNTHESIS OF CYCLOPROPANE AMINO ACIDS AND PEPTIDES | THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1992-03-18 | — | — | EP | claimed |