Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1C | Q14123 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 5/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | HTR2B | P41595 | 3/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6926221 | 1.00 | PDE1C (0.47) | PDE1CALDH1A1KDM4EBRD4POLB | |
| SCHEMBL9665674 | 0.74 | ALDH1A1 (0.48) | PDE1CALDH1A1KDM4EBRD4POLB | |
| SCHEMBL9026912 | 0.73 | PDE1C (0.43) | PDE1CALDH1A1KDM4EBRD4POLB | |
| SCHEMBL6580824 | 0.71 | EPHX1 (0.36) | POLB | |
| SCHEMBL9027378 | 0.69 | ALDH1A1 (0.50) | PDE1CALDH1A1KDM4EBRD4POLB | |
| SCHEMBL9665683 | 0.69 | PDE1C (0.47) | PDE1CALDH1A1KDM4EBRD4POLB | |
| SCHEMBL9703341 | 0.68 | HTR2C (0.60) | ALDH1A1KDM4EBRD4POLBCREBBP | |
| SCHEMBL19180060 | 0.66 | HTR2C (0.51) | ALDH1A1KDM4EBRD4POLBCREBBP | |
| SCHEMBL20558927 | 0.66 | HTR2C (0.59) | PDE1CALDH1A1KDM4EBRD4POLB | |
| SCHEMBL10253774 | 0.66 | HTR2C (0.59) | PDE1CALDH1A1KDM4EBRD4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518435-B1 | Production method, a method of producing a compound represented by the formula (III) production method of oxyimino- alkanoic acid derivatives having an anti-diabetic activity. | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-1227081-A1 | PROCESS FOR THE PREPARATION OF OXYIMINOALKANOIC ACID DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2002-07-31 | — | — | EP | disclosed |