Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4392106 | 1.00 | PTGS1 (0.46) | PTGS1PTGS2G6PC1MAOAMAOB | |
| SCHEMBL4387109 | 0.79 | PTGS1 (0.42) | PTGS1PTGS2G6PC1MAOAMAOB | |
| SCHEMBL9188391 | 0.79 | PTGS1 (0.42) | PTGS1PTGS2G6PC1MAOAMAOB | |
| SCHEMBL13509603 | 0.79 | PTGS1 (0.46) | PTGS1PTGS2G6PC1MAOAMAOB | |
| SCHEMBL8284900 | 0.71 | — | — | |
| SCHEMBL9823473 | 0.71 | ALDH1A1 (0.35) | ALDH1A1CYP3A4RECQL | |
| SCHEMBL9520363 | 0.69 | MAOA (0.51) | PTGS1PTGS2MAOAMAOBALDH1A1 | |
| SCHEMBL77016 | 0.69 | MAPK1 (0.56) | PTGS1PTGS2MAOAMAOBALDH1A1 | |
| SCHEMBL9520373 | 0.69 | MAOA (0.51) | PTGS1PTGS2MAOAMAOBALDH1A1 | |
| SCHEMBL16795760 | 0.68 | PTGS1 (0.43) | PTGS1PTGS2G6PC1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145868-A | 7-((Hydroxy(3-hydroxy-4-acylphenyl)alkylene)thio-),4-oxo-4H -chromene; antiallergens; leukotrienes antagonist | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| EP-0419410-A2 | Alkanophenones | CIBA-GEIGY AG (CH) | 1991-03-27 | — | — | EP | disclosed |