Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9669290 | 0.76 | ACHE (0.38) | ACHELMNA | |
| SCHEMBL9669263 | 0.74 | PDE10A (0.44) | SMN1; SMN2KDM4ETP53MEN1KMT2A | |
| SCHEMBL8997331 | 0.73 | ACHE (0.44) | ACHEKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL8997349 | 0.73 | ACHE (0.44) | ACHEKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL9667103 | 0.71 | ELANE (0.43) | SMN1; SMN2KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL9713992 | 0.69 | CES1 (0.47) | ACHEKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL9667222 | 0.69 | CES1 (0.47) | ACHEKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL8997328 | 0.68 | ACHE (0.42) | ACHEUSP2 | |
| SCHEMBL9713984 | 0.67 | CES1 (0.45) | ACHEKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL9713987 | 0.67 | CES1 (0.45) | ACHEKDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511366-A1 | CHEMILUMINESCENT COMPOUNDS | BECKMAN INSTRUMENTS, INC. (US) | 1992-11-04 | — | — | EP | disclosed |
| WO-1992009580-A1 | CHEMILUMINESCENT COMPOUNDS | BECKMAN INSTRUMENTS, INC. (US) | 1992-06-11 | — | — | WO | disclosed |