SCHEMBL9669290

SCHEMBL9669290

C[n+]1c2ccccc2c(C(=O)n2cccc2)c2ccccc21.O=S(=O)([O-])F

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ACHE P22303 14/20 0.38
LMNA P02545 1/20 0.32
TERT O14746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9714042 0.89 ACHE (0.46) ACHETERT
SCHEMBL8997331 0.82 ACHE (0.44) ACHE
SCHEMBL8997349 0.82 ACHE (0.44) ACHE
SCHEMBL9667103 0.82 ELANE (0.43)
SCHEMBL9713992 0.77 CES1 (0.47) ACHETERT
SCHEMBL9667222 0.77 CES1 (0.47) ACHETERT
SCHEMBL9667129 0.76 ACHE (0.35) ACHELMNA
SCHEMBL8997328 0.76 ACHE (0.42) ACHE
SCHEMBL9713984 0.76 CES1 (0.45) ACHETERT
SCHEMBL9713987 0.76 CES1 (0.45) ACHETERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0511366-A1 CHEMILUMINESCENT COMPOUNDS BECKMAN INSTRUMENTS, INC. (US) 1992-11-04 EP disclosed
WO-1992009580-A1 CHEMILUMINESCENT COMPOUNDS BECKMAN INSTRUMENTS, INC. (US) 1992-06-11 WO disclosed