SCHEMBL9667282

SCHEMBL9667282

CCCCc1nc2c(OC)ncnc2n1Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 6/20 0.54
AGTR2 P50052 6/20 0.54
AGT P01019 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9669078 0.88 AGTR1 (0.55) AGTR1AGTR2AGT
SCHEMBL9705259 0.83 AGT (0.57) AGTR1AGTR2AGT
SCHEMBL13037616 0.83 AGTR1 (0.62) AGTR1AGTR2AGT
SCHEMBL9854421 0.82 AGTR1 (0.62) AGTR1AGTR2AGT
SCHEMBL9704017 0.82 AGTR1 (0.55) AGTR1AGTR2AGT
SCHEMBL9851423 0.82 AGT (0.60) AGTR1AGTR2AGT
SCHEMBL6711100 0.80 AGTR1 (0.59) AGTR1AGTR2AGT
SCHEMBL8392437 0.80 AGTR1 (0.60) AGTR1AGTR2AGT
SCHEMBL7007240 0.80 AGT (0.53) AGTR1AGTR2AGT
SCHEMBL9667292 0.80 AGTR1 (0.39) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0467207-A2 Purinderivate F. HOFFMANN-LA ROCHE AG (CH) 1992-01-22 EP disclosed