Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9669058 | 0.92 | CYP2C19 (0.43) | XDHHPGDALDH1A1MAPKAPK2KDM4E | |
| SCHEMBL9669742 | 0.84 | XDH (0.58) | XDHHPGDALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL26049346 | 0.81 | GDA (0.35) | XDHKDM4EGLA | |
| SCHEMBL26049365 | 0.80 | XDH (0.39) | XDH | |
| SCHEMBL26348161 | 0.79 | SMN1; SMN2 (0.48) | XDHHPGDSMN1; SMN2RAB9AMAPK10 | |
| SCHEMBL26049393 | 0.78 | HPRT1 (0.35) | XDH | |
| SCHEMBL11901381 | 0.77 | GDA (0.44) | HPGDALDH1A1POLBKDM4EGLA | |
| SCHEMBL9667342 | 0.75 | XDH (0.49) | XDHALDH1A1LMNAKDM4E | |
| SCHEMBL9668908 | 0.75 | XDH (0.50) | XDHALDH1A1KDM4EHSD17B10 | |
| SCHEMBL27741454 | 0.74 | DEGS1 (0.50) | XDHHPGDALDH1A1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0467207-A2 | Purinderivate | F. HOFFMANN-LA ROCHE AG (CH) | 1992-01-22 | — | — | EP | disclosed |