Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9669758 | 0.83 | XDH (0.50) | XDHGPR84LMNA | |
| SCHEMBL9667337 | 0.75 | XDH (0.50) | XDHKDM4EALDH1A1LMNA | |
| SCHEMBL5564893 | 0.74 | DNM2 (0.47) | XDHALDH1A1LMNAADORA2A | |
| SCHEMBL17845811 | 0.70 | NPC1 (0.40) | MEN1KMT2AGPR84 | |
| SCHEMBL4442003 | 0.70 | XDH (0.46) | XDHKDM4EGAAMEN1KMT2A | |
| SCHEMBL5996030 | 0.70 | GRIN2D (0.58) | KDM4EGAAMEN1KMT2AGPR84 | |
| SCHEMBL24846526 | 0.69 | GPR84 (0.50) | XDHGPR84 | |
| SCHEMBL11035691 | 0.69 | DNM2 (0.40) | GPR84ALDH1A1LMNAADORA2A | |
| SCHEMBL24937838 | 0.68 | GRIN2D (0.56) | KDM4EGAAMEN1KMT2AGPR84 | |
| SCHEMBL11901381 | 0.68 | GDA (0.44) | KDM4EGAAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0467207-A2 | Purinderivate | F. HOFFMANN-LA ROCHE AG (CH) | 1992-01-22 | — | — | EP | disclosed |