SCHEMBL966752

SCHEMBL966752

Brc1ccc(-n2c3ccccc3c3cnccc32)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.50
MAOB P27338 4/20 0.50
ACHE P22303 2/20 0.50
KDM4E B2RXH2 1/20 0.48
ATM Q13315 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
CYP2D6 P10635 1/20 0.43
DDB1 Q16531 1/20 0.39
CRBN Q96SW2 1/20 0.39
MEN1 O00255 1/20 0.38
NPC1 O15118 1/20 0.38
LMNA P02545 1/20 0.38
GLA P06280 1/20 0.38
NFKB1 P19838 1/20 0.38
RAB9A P51151 1/20 0.38
NFKB2 Q00653 1/20 0.38
KMT2A Q03164 1/20 0.38
RELA Q04206 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1964978 0.95 MAOA (0.47) MAOAMAOBACHEKDM4EATM
SCHEMBL4570443 0.87 MAOA (0.53) MAOAMAOBACHEKDM4EATM
SCHEMBL15907062 0.87 MAOA (0.53) MAOAMAOBACHEKDM4EATM
SCHEMBL12098614 0.86 KDM4E (0.67) MAOAMAOBACHEKDM4EATM
SCHEMBL5021388 0.86 MAOA (0.49) MAOAMAOBACHEKDM4EATM
SCHEMBL6113993 0.86 MAOA (0.49) MAOAMAOBACHEKDM4EATM
SCHEMBL6114327 0.86 MAOA (0.43) MAOAMAOBACHEKDM4EATM
SCHEMBL29400116 0.84 KDM4E (0.67) ACHEKDM4EATML3MBTL1MEN1
SCHEMBL262160 0.84 KDM4E (0.67) ACHEKDM4EATML3MBTL1MEN1
SCHEMBL11978692 0.84 MAOA (0.50) MAOAMAOBACHEKDM4EATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9755152-B2 Compound having substituted anthracene ring structure and pyridoindole ring structure, and organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2017-09-05 US disclosed
EP-2336130-B1 COMPOUND HAVING SUBSTITUTED ANTHRACENE RING STRUCTURE AND PYRIDOINDOLE RING STRUCTURE AND ORGANIC ELECTROLUMINESCENCE DEVICE HODOGAYA CHEMICAL CO LTD (JP) 2017-06-28 EP disclosed
US-20150155496-A1 COMPOUND HAVING SUBSTITUTED ANTHRACENE RING STRUCTURE AND PYRIDOINDOLE RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO LTD (JP) 2015-06-04 US disclosed
EP-2463287-B1 COMPOUND HAVING SUBSTITUTED ANTHRACENE RING STRUCTURE AND PYRIDOINDOLE RING STRUCTURE AND ORGANIC ELECTROLUMINESCENCE DEVICE HODOGAYA CHEMICAL CO LTD (JP) 2015-03-18 EP disclosed
US-8927119-B2 Compound having substituted anthracene ring structure and pyridoindole ring structure, and organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2015-01-06 US disclosed
EP-2241568-B1 COMPOUND HAVING SUBSTITUTED PYRIDYL GROUP AND PYRIDOINDOLE RING STRUCTURE LINKED THROUGH PHENYLENE GROUP, AND ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO LTD (JP) 2014-09-10 EP disclosed
EP-2463288-B1 Compound having substituted pyridyl group and pyridoindole ring structure linked through phenylene group, and organic electroluminescent device HODOGAYA CHEMICAL CO LTD (JP) 2014-09-10 EP disclosed
US-20130341604-A1 COMPOUND HAVING SUBSTITUTED ANTHRACENE RING STRUCTURE AND PYRIDOINDOLE RING STRUCTURE AND ORGANIC ELECTROLUMINESCENCE DEVICE HODOGAYA CHEMICAL CO LTD (JP) 2013-12-26 US disclosed
US-8586210-B2 Compound having substituted anthracene ring structure and pyridoindole ring structure and organic electroluminescence device HODOGAYA CHEMICAL CO., LTD. (JP) 2013-11-19 US disclosed
US-8377573-B2 Compound having substituted pyridyl group and pyridoindole ring structure linked through phenylene group, and organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2013-02-19 US disclosed
EP-2463288-A1 Compound having substituted pyridyl group and pyridoindole ring structure linked through phenylene group, and organic electroluminescent device Hodogaya Chemical Co., Ltd. (JP) 2012-06-13 EP disclosed
EP-2463287-A1 COMPOUND HAVING SUBSTITUTED ANTHRACENE RING STRUCTURE AND PYRIDOINDOLE RING STRUCTURE AND ORGANIC ELECTROLUMINESCENCE DEVICE Hodogaya Chemical Co., Ltd. (JP) 2012-06-13 EP disclosed
US-20120126220-A1 COMPOUND HAVING SUBSTITUTED ANTHRACENE RING STRUCTURE AND PYRIDOINDOLE RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2012-05-24 US disclosed
US-20110175079-A1 COMPOUND HAVING SUBSTITUTED ANTHRACENE RING STRUCTURE AND PYRIDOINDOLE RING STRUCTURE AND ORGANIC ELECTROLUMINESCENCE DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2011-07-21 US disclosed
EP-2336130-A1 COMPOUND HAVING SUBSTITUTED ANTHRACENE RING STRUCTURE AND PYRIDOINDOLE RING STRUCTURE AND ORGANIC ELECTROLUMINESCENCE DEVICE Hodogaya Chemical Co., Ltd. (JP) 2011-06-22 EP disclosed
US-20110006291-A1 COMPOUND HAVING SUBSTITUTED PYRIDYL GROUP AND PYRIDOINDOLE RING STRUCTURE LINKED THROUGH PHENYLENE GROUP, AND ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO. LTD. (JP) 2011-01-13 US disclosed
EP-2241568-A1 COMPOUND HAVING SUBSTITUTED PYRIDYL GROUP AND PYRIDOINDOLE RING STRUCTURE LINKED THROUGH PHENYLENE GROUP, AND ORGANIC ELECTROLUMINESCENT DEVICE Hodogaya Chemical Co., Ltd. (JP) 2010-10-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150155496-A1 COMPOUND HAVING SUBSTITUTED ANTHRACENE RING STRUCTURE AND PYRIDOINDOLE RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE SLCO2B1, PNPO, SLCO2A1 MAOA 314/4885MAOB 226/4885ACHE 406/4885
US-20110006291-A1 COMPOUND HAVING SUBSTITUTED PYRIDYL GROUP AND PYRIDOINDOLE RING STRUCTURE LINKED THROUGH PHENYLENE GROUP, AND ORGANIC ELECTROLUMINESCENT DEVICE KCNH3, KCNH2, CHRNA9 MAOA 599/4885MAOB 360/4885ACHE 1227/4885
US-20120126220-A1 COMPOUND HAVING SUBSTITUTED ANTHRACENE RING STRUCTURE AND PYRIDOINDOLE RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE SLCO2B1, PNPO, SLCO2A1 MAOA 314/4885MAOB 226/4885ACHE 406/4885
US-20110175079-A1 COMPOUND HAVING SUBSTITUTED ANTHRACENE RING STRUCTURE AND PYRIDOINDOLE RING STRUCTURE AND ORGANIC ELECTROLUMINESCENCE DEVICE SLCO2A1, SLCO2B1, SLCO4C1 MAOA 279/4885MAOB 124/4885ACHE 881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.