SCHEMBL966811

SCHEMBL966811

CC(C)OC(=O)CCS.CC(C)OC(=O)CCS.[Zn]

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.52
ACE P12821 1/20 0.41
TSHR P16473 3/20 0.40
MAPT P10636 3/20 0.39
HTT P42858 1/20 0.36
CYP2D6 P10635 1/20 0.34
NOTUM Q6P988 1/20 0.34
ALDH1A1 P00352 2/20 0.33
HSD17B10 Q99714 2/20 0.33
GAA P10253 1/20 0.33
EPHX2 P34913 1/20 0.33
ALOX15 P16050 1/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5829654 0.98
SCHEMBL304069 0.84 LMNA (0.61) LMNATSHRMAPTHTTALDH1A1
SCHEMBL29449633 0.83 ACE (0.46) LMNAACETSHRMAPTALDH1A1
SCHEMBL6741044 0.82 LMNA (0.64) LMNATSHRMAPTALDH1A1HSD17B10
SCHEMBL72471 0.82 LMNA (0.62) LMNATSHRMAPTHTTCYP2D6
SCHEMBL963289 0.80 TSHR (0.48) LMNATSHRMAPTCYP2D6ALDH1A1
SCHEMBL31402602 0.79 LMNA (0.60) LMNATSHRMAPTHTTCYP2D6
SCHEMBL11965900 0.77 ACE (0.42) LMNAACETSHRHSD17B10
SCHEMBL10827167 0.77 ACE (0.46) LMNAACEALDH1A1
SCHEMBL6739872 0.77 LMNA (0.39) LMNAACETSHRMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2280057-B2 LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE IDEMITSU KOSAN CO (JP) 2016-11-23 EP disclosed
US-9321981-B2 Lubricating oil composition for internal combustion engine IDEMITSU KOSAN CO., LTD. (JP) 2016-04-26 US disclosed
EP-2280057-B1 LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE IDEMITSU KOSAN CO (JP) 2013-09-11 EP disclosed
EP-2280057-A1 LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE Idemitsu Kosan Co., Ltd. (JP) 2011-02-02 EP disclosed
US-20110021393-A1 LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE IDEMITSU KOSAN CO., LTD. (JP) 2011-01-27 US disclosed