Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 4/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4904230 | 0.88 | LMNA (0.46) | LMNAEPHX2CA12CA1CA2 | |
| SCHEMBL645070 | 0.86 | CA12 (0.45) | LMNAEPHX2CA12CA1CA2 | |
| SCHEMBL6741287 | 0.86 | LMNA (0.48) | LMNAEPHX2CA12CA1CA2 | |
| SCHEMBL2989645 | 0.82 | ALDH1A1 (0.50) | LMNAEPHX2CA12CA1CA2 | |
| SCHEMBL10554751 | 0.82 | LMNA (0.57) | LMNAEPHX2CA12CA1CA2 | |
| SCHEMBL1585214 | 0.82 | ALDH1A1 (0.50) | LMNAEPHX2CA12CA1CA2 | |
| SCHEMBL2980900 | 0.82 | ALDH1A1 (0.50) | LMNAEPHX2CA12CA1CA2 | |
| SCHEMBL6231000 | 0.82 | LMNA (0.52) | LMNAEPHX2CA12CA1CA2 | |
| SCHEMBL6741077 | 0.82 | — | — | |
| SCHEMBL13341730 | 0.81 | EPHX2 (0.38) | LMNAEPHX2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9012127-B2 | Thermoreversible network scaffolds and methods of preparing same | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2015-04-21 | — | — | US | disclosed |
| US-20130244179-A1 | Novel Thermoreversible Network Scaffolds and Methods of Preparing Same | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2013-09-19 | — | — | US | disclosed |
| WO-2012074994-A1 | NOVEL THERMOREVERSIBLE NETWORK SCAFFOLDS AND METHODS OF PREPARING SAME | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2012-06-07 | — | — | WO | disclosed |
| US-20040043903-A1 | Herbicides; applying to plants | BASF AKTIENGESELLSCHAFT (DE) | 2004-03-04 | — | — | US | disclosed |
| US-20040023807-A1 | 3-Arylisothiazoles and their use as herbicides | BASF AKTIENGESELLSCHAFT (DE) | 2004-02-05 | — | — | US | disclosed |
| US-20030216257-A1 | 1-aryl-4-alkyl halide-2(1h)-pyridones and their use as herbicides | BASF AKTIENGESELLSCHAFT (DE) | 2003-11-20 | — | — | US | disclosed |
| EP-1335903-A1 | 2-ARYL-5-TRIFLUOROMETHYLPYRIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2003-08-20 | — | — | EP | disclosed |
| WO-2002042275-A1 | 2-ARYL-5-TRIFLUOROMETHYLPYRIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2002-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040023807-A1 | 3-Arylisothiazoles and their use as herbicides | DDT, HAX1, SULT1E1 | LMNA 4564/4885EPHX2 2749/4885ACE 777/4885 |
| US-20040043903-A1 | Herbicides; applying to plants | DDT, DRD1, DRD4 | LMNA 4573/4885EPHX2 1056/4885ACE 516/4885 |
| US-20030216257-A1 | 1-aryl-4-alkyl halide-2(1h)-pyridones and their use as herbicides | CYP1B1, DDT, CYP1A1 | LMNA 3218/4885EPHX2 1207/4885ACE 408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.