Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9666946 | 0.91 | RAB9A (0.47) | RAB9AMAPTHTTNPSR1NPC1 | |
| SCHEMBL9668220 | 0.90 | RAB9A (0.49) | RAB9AMAPTHTTNPSR1NPC1 | |
| SCHEMBL9668140 | 0.88 | RAB9A (0.47) | RAB9AMAPTHTTNPSR1NPC1 | |
| SCHEMBL9666921 | 0.86 | RAB9A (0.47) | RAB9AMAPTHTTNPSR1NPC1 | |
| SCHEMBL9668158 | 0.83 | RAB9A (0.47) | RAB9AMAPTHTTNPSR1NPC1 | |
| SCHEMBL9666917 | 0.81 | RAB9A (0.47) | RAB9AMAPTHTTNPSR1NPC1 | |
| SCHEMBL9666937 | 0.81 | RAB9A (0.47) | RAB9AMAPTHTTNPSR1NPC1 | |
| SCHEMBL9666913 | 0.81 | RAB9A (0.47) | RAB9AMAPTHTTNPSR1NPC1 | |
| SCHEMBL7642680 | 0.79 | RAB9A (0.56) | RAB9AMAPTHTTNPSR1NPC1 | |
| SCHEMBL8716892 | 0.79 | RAB9A (0.61) | RAB9AMAPTNPC1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219923-B1 | ANTIBIOTIC DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1992-09-02 | — | — | EP | claimed |
| EP-0219923-B1 | ANTIBIOTIC DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1992-09-02 | — | — | EP | disclosed |
| US-4851422-A | Antibiotic 2-(3-oxo-2-isoxazolidinyl)-5-oxo-2-tetrahydrofuran-carboxylates | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-07-25 | — | — | US | disclosed |
| EP-0219923-A1 | Antibiotic derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-04-29 | — | — | EP | disclosed |