Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7642680 | 0.91 | RAB9A (0.56) | RAB9ANPC1TDP1IDO1CYP1A2 | |
| SCHEMBL6151831 | 0.90 | RAB9A (0.61) | RAB9ANPC1TDP1IDO1CYP1A2 | |
| SCHEMBL6645015 | 0.90 | RAB9A (0.61) | RAB9ANPC1TDP1IDO1CYP1A2 | |
| SCHEMBL7058021 | 0.88 | ALDH1A1 (0.57) | RAB9ANPC1TDP1ATMALDH1A1 | |
| SCHEMBL7058146 | 0.88 | ALDH1A1 (0.57) | RAB9ANPC1TDP1ATMALDH1A1 | |
| SCHEMBL11419632 | 0.88 | IDO1 (0.56) | RAB9AIDO1CYP1A2CYP2C19AKR1C3 | |
| SCHEMBL11061953 | 0.87 | ALOX5 (0.62) | RAB9ANPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL11099610 | 0.86 | IDO1 (0.58) | RAB9AIDO1AKR1C3ALDH1A1MAPT | |
| SCHEMBL11688696 | 0.86 | ALDH1A1 (0.70) | RAB9ANPC1TDP1ALDH1A1MEN1 | |
| SCHEMBL6659912 | 0.86 | ALDH1A1 (0.70) | RAB9ANPC1TDP1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5834486-A | ANTIPROLIFERATIVE, ANTIPROTOZOA AGENTS | NOVARTIS AG (CH) | 1998-11-10 | — | — | US | disclosed |
| US-5149802-A | Chemical intermediates for antibiotics | MERCIAN CORPORATION (JP) | 1992-09-22 | — | — | US | disclosed |
| US-5096899-A | Nonhydrolyzing oxapenicillins | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-17 | — | — | US | disclosed |
| EP-0163433-B1 | ANTIBACTERIAL SOLID COMPOSITION FOR ORAL ADMINISTATION | Takeda Chemical Industries, Ltd. (JP) | 1990-08-01 | — | — | EP | disclosed |
| US-4725678-A | ANTIBIOTICS | PFIZER INC. (US) | 1988-02-16 | — | — | US | disclosed |
| US-4595539-A | Containing acid or ester groups and sulfur | PFIZER INC. (US) | 1986-06-17 | — | — | US | disclosed |
| EP-0128725-A1 | Preparation of penem derivatives | PFIZER INC. (US) | 1984-12-19 | — | — | EP | disclosed |
| EP-0008888-B1 | BETA-LACTAM ANTIBACTERIAL COMPOUNDS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1983-09-21 | — | — | EP | disclosed |
| EP-0008888-A1 | Beta-lactam antibacterial compounds, their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1980-03-19 | — | — | EP | disclosed |