Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL870631 | 0.81 | KMT2A (0.59) | SMN1; SMN2GAAKMT2AMEN1RAB9A | |
| SCHEMBL6545595 | 0.80 | KMT2A (0.62) | SMN1; SMN2GAAKMT2AMEN1RAB9A | |
| SCHEMBL13967296 | 0.78 | HTT (0.50) | SMN1; SMN2GAAKMT2AMEN1RAB9A | |
| SCHEMBL9669729 | 0.77 | GAA (0.70) | SMN1; SMN2GAAKMT2AMEN1RAB9A | |
| SCHEMBL2561496 | 0.76 | KMT2A (0.54) | SMN1; SMN2GAAKMT2AMEN1RAB9A | |
| SCHEMBL2561497 | 0.76 | KMT2A (0.54) | SMN1; SMN2GAAKMT2AMEN1RAB9A | |
| SCHEMBL5339837 | 0.76 | ALDH1A1 (0.61) | SMN1; SMN2GAAKMT2AMEN1RAB9A | |
| SCHEMBL24629305 | 0.75 | KMT2A (0.72) | SMN1; SMN2GAAKMT2AMEN1RAB9A | |
| SCHEMBL27136868 | 0.75 | KMT2A (0.72) | SMN1; SMN2GAAKMT2AMEN1RAB9A | |
| SCHEMBL3866851 | 0.75 | ALDH1A1 (0.73) | SMN1; SMN2GAAKMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299973-B1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1992-06-17 | — | — | EP | claimed |
| EP-0299973-A1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS. | UPJOHN CO (US) | 1989-01-25 | — | — | EP | claimed |
| WO-1987006133-A1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1987-10-22 | — | — | WO | claimed |