Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.60 |
| ▸ | MEN1 | O00255 | 8/20 | 0.60 |
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1255026 | 0.85 | ALDH1A1 (0.65) | ALDH1A1IMPDH2KMT2AMEN1MAPT | |
| SCHEMBL14214887 | 0.84 | ALDH1A1 (0.62) | ALDH1A1IMPDH2KMT2AMEN1MAPT | |
| SCHEMBL10258636 | 0.84 | ALDH1A1 (0.62) | ALDH1A1IMPDH2KMT2AMEN1MAPT | |
| SCHEMBL27347145 | 0.79 | ALDH1A1 (0.67) | ALDH1A1IMPDH2KMT2AMEN1MAPT | |
| SCHEMBL212576 | 0.79 | KMT2A (0.57) | ALDH1A1IMPDH2KMT2AMEN1MAPT | |
| SCHEMBL212575 | 0.79 | KMT2A (0.57) | ALDH1A1IMPDH2KMT2AMEN1MAPT | |
| SCHEMBL10531462 | 0.77 | ALDH1A1 (0.69) | ALDH1A1IMPDH2KMT2AMEN1MAPT | |
| SCHEMBL212837 | 0.76 | MAPT (0.54) | ALDH1A1IMPDH2KMT2AMEN1MAPT | |
| SCHEMBL9668352 | 0.76 | SMN1; SMN2 (0.66) | ALDH1A1KMT2AMEN1MAPTRAB9A | |
| SCHEMBL20709686 | 0.76 | MAPT (0.54) | ALDH1A1IMPDH2KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110790695-B | Synthesis and application of benzil hydrazone-N-methyl-3-indole formaldehyde | 齐鲁工业大学 | 2023-04-11 | — | — | CN | claimed |
| CN-113855673-A | Application of bispyridone hydrazone-N-methyl-3-indole formaldehyde Schiff base | 齐鲁工业大学 | 2021-12-31 | — | — | CN | claimed |
| CN-110790695-B | Synthesis and application of benzil hydrazone-N-methyl-3-indole formaldehyde | 齐鲁工业大学 | 2023-04-11 | — | — | CN | disclosed |
| CN-113855673-A | Application of bispyridone hydrazone-N-methyl-3-indole formaldehyde Schiff base | 齐鲁工业大学 | 2021-12-31 | — | — | CN | disclosed |
| US-20070060605-A1 | Compositions and methods for inhibiting platelet activation and thrombosis | FLAUMENHAFT ROBERT C | 2007-03-15 | — | — | US | disclosed |
| US-7166612-B2 | Methods for reducing platelet activation platelet aggregaton or thrombosis | BETH ISRAEL DEACONESS MEDICAL CENTER (US) | 2007-01-23 | — | — | US | disclosed |
| US-20040147540-A1 | Compositions and methods for inhibiting platelet activation and thrombosis | BETH ISRAEL DEACONESS MEDICAL CENTER | 2004-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060605-A1 | Compositions and methods for inhibiting platelet activation and thrombosis | PLA2G7, PLTP, PLAAT2 | ALDH1A1 2786/4885IMPDH2 4482/4885KMT2A 3252/4885 |
| US-20040147540-A1 | Compositions and methods for inhibiting platelet activation and thrombosis | PLA2G7, PLTP, PLAAT2 | ALDH1A1 2786/4885IMPDH2 4482/4885KMT2A 3252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.