Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | BAD | Q92934 | 1/20 | 0.37 |
| ▸ | NQO1 | P15559 | 3/20 | 0.35 |
| ▸ | CTRC | Q99895 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.32 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL368712 | 0.83 | BCL2L1 (0.41) | BCL2L1BADNQO1CTRCADRA2A | |
| SCHEMBL2787728 | 0.79 | SELL (0.47) | BCL2L1BADNQO1CTRCMAPK1 | |
| SCHEMBL4906016 | 0.76 | ALDH1A1 (0.47) | BCL2L1BADNQO1CTRCGRIA1 | |
| SCHEMBL23713391 | 0.75 | SELL (0.47) | BCL2L1BADMAPK1MEN1KMT2A | |
| SCHEMBL7208190 | 0.73 | ALDH1A1 (0.47) | BCL2L1BADNQO1MAPK1L3MBTL1 | |
| SCHEMBL6416867 | 0.72 | PDK2 (0.42) | BCL2L1BADPDK1PDK2PDK3 | |
| SCHEMBL27350945 | 0.69 | HSP90AB1 (0.42) | BCL2L1BADNQO1MAPK1MEN1 | |
| SCHEMBL19330760 | 0.69 | PDK2 (0.42) | PDK1PDK2PDK3PDK4MEN1 | |
| SCHEMBL6291628 | 0.68 | ALDH1A1 (0.47) | — | |
| SCHEMBL6436615 | 0.68 | HSD17B10 (0.41) | BCL2L1BADMAPK1NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470221-A1 | NEW ARYL- AND HETEROARYLETHENYLENE DERIVATIVES AND PROCESS FOR THEIR PREPARATION. | ERBA CARLO SPA (IT) | 1992-02-12 | — | — | EP | disclosed |